Side effects of GLP-1 medications.. What are their causes?

Some women spoke about the side effects they suffered from using GLP-1 medications, while two female doctors explained one of the most prominent causes. Side effects of using GLP-1 drugs include: But the women stressed that each person's response is very different, with one saying: "Two people can be exactly the same height, weight, and the dose they take, and yet their bodies respond to the drug in a completely different way."

For example, one patient reported that GLP-1 increased her anxiety, while it decreased it in another. Diarrhea is “a very common side effect with any of the GLP-1 medications, especially if you eat fatty or fried foods,” said Dr. Rocio Salas Wallen, an endocrinologist and obesity specialist.

“Many patients eat pizza or go out to eat, and then have a bout of diarrhea the next day.” Dr. Holly Lofton, a researcher and specialist in obesity medicine, explained that one of the effects of GLP-1 drugs is that they slow the rate at which the stomach empties its contents.

“When you add high-fat foods along with that, it slows down stomach emptying even more,” she said. “And when you add alcohol to that, it slows down stomach emptying even more.”

That's why Lofton advises her patients not to "combine fatty foods with alcohol, because this increases the risk of vomiting, as the stomach does not empty its contents as it should."